He was 63 years old (he was born in 1507).
A cultured man and member of the Accademia della Fama, he eschewed mercantile activities and was a patron of science, letters and the arts.
He held numerous diplomatic posts and was among other things ambassador to Emperor Charles V and Popes Paul IV and Pius IV, and finally from 17 February 1565 m.v. procurator of S. Marco de ultra.
His dogado was not a serene one, he saw victory over the Turks at Lepanto (1571), but also the less than honourable peace that, due to the dissolution of the Christian League, sanctioned the loss of Cyprus, the burning of the Doge's Palace (1574) and the arrival in Venice, in the same year of Henry III of Poland (in transit from Venice to take the crown of King of France), but also a terrible plague (1575) that, after claiming almost 50,000 victims, subsided and the Republic decided to build a votive temple dedicated to the Redeemer.
He was buried next to his wife Loredana Marcello in the Church of S. Giovanni e Paolo (Castello): the family tomb occupies the counter-façade of the church. The monument was begun in 1580 by G. Grapiglia and completed in 1646 by F. Contin.
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